MuriGenics specializes in rodent preclinical non-GLP toxicology studies, directed toward preliminary screening and safety profiling of test articles.
As with all of our in vivo services, we guarantee continued communication during on-going studies and will contact you directly with any questions or concerns. This guarantees that any data collected is both biologically and clinically reliable and relevant. Further, any valued data that appears to warrant a change in protocol can be discussed, giving the client the flexibility to modify their existing protocols.
Species
Mice (outbred, inbred, genetically engineered strains, contact us for additional information on a specific strain or with questions regarding strains that may express a specific phenotype of interest)
Rats (implanted catheters available, inquire about strains)
Means of Administration:
- Oral
- Intranasal
- Intravenous
-
Continuous Infusions
(Osmotic or syringe pump)
- Subcutaneous
- Intratracheal
- Topical
- Slow-Infusion
- Intraperitoneal
- Intramuscular
- Intrathecal
- Oral
- Intraperitoneal
- Intratracheal
- Intravenous
- Intrathecal
-
Continuous Infusions
(Osmotic or syringe pump)
- Subcutaneous
- Intranasal
- Intramuscular
- Topical
- Slow-Infusion
Observations/Endpoints
Some of the study observations/endpoints are – Clinical observation (Irwin’s test), Body weight, Tumor volume measurements, Tumor imaging – fluorescence and luminescence, CBC, Blood biochemistry, cell phenotyping – flow analysis, cytokine analysis, tissue bio-distribution etc..